role of angiotensin type 2 receptor on nitric oxide production response to angiotensin ii administration in ovariectomised rats treated with estradiol
نویسندگان
چکیده
-
منابع مشابه
The Role of Mas Receptor and Bradykinin on Nitric Oxide Production Response to Angiotensin 1-7 in Ovariectomized Rats Treated with Estradiol
Introduction: The angiotensin 1-7 (Ang1-7) Mas receptor (MasR) axis, bradykinin (BK) and female sex hormone are involved in releasing of vasodilatory biomarkers including Nitric Oxide (NO). We examined the role of MasR and BK on NO metabolite (nitrite) production response to Ang 1-7 infusion in ovariectomized rats treated with estradiol. Methods: A total of 48 female Wistar rats were divided i...
متن کاملrole of mas receptor in renal blood flow response to angiotensin-(1-7) in ovariectomized estradiol treated rats
the angiotensin 1-7 (ang 1-7), is abundantly produced in kidneys and antagonizes the function of angiotensin ii through mas receptor (masr) or other unknown mechanisms. in the current study, the role of masr and steroid hormone estrogen on renal blood flow response to ang 1-7 administration was investigated in ovariectomized (ov) female rats. ov female wistar-rats received estradiol (500 µg/kg/...
متن کاملAngiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor.
We previously reported that angiotensin II stimulates an increase in nitric oxide production in pulmonary artery endothelial cells. The aims of this study were to determine which receptor subtype mediates the angiotensin II-dependent increase in nitric oxide production and to investigate the roles of the angiotensin type 1 and type 2 receptors in modulating angiotensin II-dependent vasoconstric...
متن کاملRole of bradykinin, nitric oxide, and angiotensin II type 2 receptor in imidapril-induced angiogenesis.
The angiotensin II (Ang II)-Ang II type 1 receptor pathway is proangiogenic, whereas studies showed that some angiotensin-converting enzyme inhibitors also stimulate angiogenesis in the setting of tissue ischemia, leaving a controversy of Ang II-mediated angiogenesis. We investigated whether an angiotensin-converting enzyme inhibitor imidapril-induced angiogenesis might be mediated via the tiss...
متن کاملRole of Angiotensin II in Reactive Oxygen Species Production and Modulatory Role of Nitric Oxide (NO) in Vessel Responses to AngII in Acute Joint Inflammation in the Rabbit
Introduction: It has been approved that in most tissues NO production increases during acute inflammation and Angiotensin II has a role in production of reactive oxygen species (ROS). As regulation of joint blood flow (JBF) is important in this situation, this study was performed to investigate the interaction of local Ang II and ROS production and the modulatory role of NO on regulation of JBF...
متن کاملNuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production.
Expression of nuclear angiotensin II type 1 (AT(1)) receptors in rat kidney provides further support for the concept of an intracellular renin-angiotensin system. Thus we examined the cellular distribution of renal ANG II receptors in sheep to determine the existence and functional roles of intracellular ANG receptors in higher order species. Receptor binding was performed using the nonselectiv...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
international journal of preventive medicineجلد ۵، شماره ۲، صفحات ۲۳۸-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023